According to new research, inflammatory bowel disease (IBD) and depression are linked in a compelling way.
Crohn’s disease and ulcerative colitis are examples of IBD. In addition to the physical suffering these illnesses can cause, the current study found that patients are at a higher risk of developing depression.
Surprisingly, according to the researchers, IBD-free siblings of persons with the condition were more likely to acquire depression. People with IBD were nine times more likely than the general population to develop depression, while their siblings who did not have IBD were roughly two times more likely.
According to a study recently published in the Journal of Gastroenterology and Hepatology, people with depression were two times more likely to get IBD, and their siblings without depression were more than 1.5 times more likely to develop IBD.
Dr. Bing Zhang, the co-lead author, said, “This research demonstrates a clinical overlap between both illnesses and is the first study to evaluate the two-way link between IBD and depression in siblings.” He works as a gastroenterologist at the Keck School of Medicine at the University of Southern California.
“The discovery that patients with IBD are more likely to be depressed makes sense because IBD generates chronic gastrointestinal problems that can be quite disruptive to a patient’s life,” Zhang stated in a university news release. “And, if the siblings play a role in the patient’s care, the increased depression risk among siblings of IBD patients may reflect caregiver exhaustion.”
According to Zhang, environmental stresses, the gut microbiome, and genetics are just a few of the many elements that could play a role in the two-way relationship between IBD and depresion.
He did say that the team was shocked to discover that persons with depresion are more likely to get IBD and that this could be due to the gut-brain axis, which connects the gastrointestinal system to the central nervous system, which includes the spinal cord and brain.
According to Zhang, brain inflammation, which plays a role in depression, could be linked to gastrointestinal inflammation, which is a hallmark of IBD.
IBD affects over 1.6 million Americans, while more than 16 million suffer from depression.
Author: Muhammad Asim